Endocrine Abstracts

Introduction: Diabetes is known as a risk factor of microangiopathy which generally appear concomitantly. Diabetes is also the most common cause of peripheral polyneuropathy and all these complications are related to chronic hyperglycemia. The main objective of the present study is to determine the prevalence of the diabetic peripheral neuropathy (DPN) and its characteristics in people with normoalbuminuria.Methods: Descriptive cross-sectional study cond...

Introduction : Sarcopenia is a clinical condition defined as low skeletal muscle mass and function. It has been identified and described as a geriatric syndrome, increasing the risk of frailty, comorbidities and mortality. However, sarcopenia may arise in individuals with obesity at any age. Our objective was therefore to screen for sarcopenia in a group of obese adults.Materials and methods: This was a descriptive cross-sectional study, carried out on 5...

Introduction: Sarcopenia, defined as the loss of skeletal muscle mass and function, is common for individuals with obesity due to adipose tissue disorders, metabolic changes associated with a sedentary lifestyle and during the ageing process. However, sarcopenia can occur in obese people at any age. Our objectives were therefore to screen for sarcopenia in a group of obese adults, and to identify the clinical risk factors associated with sarcopenic obesity.<p class="abstex...

Introduction : Anemia, known as a common complication in diabetic type 2 population, was observed to be an independent risk factor for the development of high-risk proliferative diabetic retinopathy. The aim of our study is to estimate the prevalence of anemia in persons with type 2 diabetes mellitus and its role as a risk factor in the presence and the severity of diabetic retinopathy, in a population based study.Methods: Descriptive cross-sectional stu...

Introduction: Insulinoma is a rare neuroendocrine tumor. Its diagnosis is clinico-biological. Preoperative topographical diagnosis is necessary to guide the therapeutic procedure.Observation: We report the case of a 37-year-old patient, without notable pathological history, who was admitted for exploration of severe hypoglycemia, not felt, evolving for 2 years and complicated by convulsive attacks. The initial etiological investigation revealed corticotr...

Introduction: Graves’ disease is a frequent endocrine disorder, often treated as first-line therapy with antithyroid drugs. Herin, we report two female patients with Methimazole allergy while detailing its management.Case Reports: TWO female patients aged respectively 27 and 28 years old were diagnosed with Graves’ disease (GD), diagnosed given the association of peripheral hyperthyroidism and elevated anti TSH receptor antibodies. The first de...

Introduction: Hashimoto’s thyroiditis (HT) is one of the most frequent endocrine diseases worldwide that is typically irreversible. Herein we report the case of a woman who had spontaneous remission of hypothyroidism while discussing the potential mechanisms underlying this unusual evolution.Case report: T.C. is a 44-year-old woman with no familial history of thyroid diseases nor auto-immune conditions. She has no particular personal medical history...

Introduction: The diabetic foot is a frequent, serious and costly complication of diabetes. The prevention of diabetic foot involves a systematic podiatric evaluation of diabetic patients to identify the foot at risk. The aim of our study was to determine the podiatric risk in a Tunisian diabetic population according to the classification of the International Working Group on the Diabetic Foot (IWGDF) and the factors associated with podiatric risk.Method...

Introduction: Diabetes mellitus (DM) is the most common endocrine disorder. The skin manifestations of diabetes can vary depending on the duration of the disease and the control of blood glucose levels. Almost all patients with DM eventually develop skin changes due to the long-term effects of hyperglycemia on microcirculation and skin collagen. This study was conducted to find the hospital based prevalence of mucocutaneous manifestations in patients with diabetes mellitus, th...

Introduction: Obesity is one of the major public health issues worldwide and is known to be associated with an increased risk of severe metabolic and cardiovascular complication. The aim of our study was to assess the impact of obesity severity on the metabolic profile of obese patients.Materials and methods: Cross-sectional descriptive study involving 68 obese patients carried within the National Institute of Nutrition in Tunis. The patients were divide...